TYLENOL® is thought to work by elevating the body's overall pain threshold, so that you feel less pain. It starts working fast, but won't irritate your stomach the way that NSAIDS (non-steroidal anti-inflammatory drugs) like aspirin, naproxen sodium, or even ibuprofen sometimes can.

Pain relievers like aspirin, naproxen sodium, and ibuprofen work by blocking a substance that carries pain messages to your brain. The problem is that same substance also protects your stomach lining, and when NSAIDs block that substance, your stomach lining is more vulnerable to bleeding and irritation. Furthermore, NSAIDs may also start a reaction that may trigger a severe asthma attack in some asthmatics.

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