• Children's Tylenol® Cold + Flu liquid medicine with acetaminophen in grape flavor
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TYLENOL® Cold + Flu + Cough Nighttime Liquid

For Relief Of Fever, Pain, Cough & Nasal Congestion

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Nighttime multi-symptom liquid relief for coughs, congestion, runny nose and sore throats, so you get the rest you need.

In September, 2023, The Nonprescription Drugs Advisory Committee of the Food and Drug Administration reviewed efficacy data available for orally administered phenylephrine (PE) as a nasal decongestant. Read the FDA’s statement about this review here.


Product details

  • temporarily relieves these common cold/flu symptoms:
    • minor aches and pains
    • headache
    • sore throat
    • nasal congestion
    • runny nose and sneezing
    • cough
    • sinus congestion and pressure
  • helps clear nasal passages
  • relieves cough to help you sleep
  • temporarily reduces fever

Ingredient Name
Acetaminophen

Ingredient Purpose
Pain reliever/fever reducer

Ingredient Name
Dextromethorphan HBr

Ingredient Purpose
Cough suppressant

Ingredient Name
Doxylamine succinate

Ingredient Purpose
Antihistamine

Ingredient Name
Phenylephrine HCl

Ingredient Purpose
Nasal decongestant

Active ingredients
Acetaminophen 325 mg in each 15 mL
Dextromethorphan HBr 10 mg in each 15 mL
Doxylamine succinate 6.25 mg in 15 mL
Phenylephrine HCl 5 mg in each 15 mL

Inactive ingredients
alcohol, anhydrous citric acid, FD&C blue no. 1, flavor, glycerin, propylene glycol, purified water, sodium benzoate, sorbitol solution, sucralose

Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
  • if you have ever had an allergic reaction to this product or any of its ingredients.

Ask a doctor before use if you have

  • liver disease
  • heart disease
  • high blood pressure
  • thyroid disease
  • diabetes
  • trouble urinating due to an enlarged prostate gland
  • a breathing problem such as emphysema or chronic bronchitis
  • glaucoma
  • persistent or chronic cough such as occurs with smoking, asthma or emphysema
  • cough that occurs with too much phlegm (mucus)

Ask a doctor or pharmacist before use if you are

  • taking the blood thinning drug warfarin
  • taking sedatives or tranquilizers

When using this product:

  • do not exceed recommended dose
  • excitability may occur, especially in children
  • marked drowsiness may occur
  • alcohol, sedatives, and tranquilizers may increase drowsiness
  • avoid alcoholic drinks
  • be careful when driving a motor vehicle or operating machinery

Stop use and ask a doctor if

  • nervousness, dizziness, or sleeplessness occur
  • pain, nasal congestion or cough gets worse or lasts more than 7 days
  • fever gets worse or lasts more than 3 days
  • redness or swelling is present
  • new symptoms occur
  • cough comes back or occurs with rash or headache that lasts

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222). Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Questions or comments? call 1-877-895-3665 (toll-free) or 215-273-8755 (collect)

This website contains current product information and may differ from the information on the product packaging you may have. If you have any questions, please contact the Consumer Care Center at 1-877-895-3665.

  • each 15 mL contains: sodium 5 mg
  • store between 20-25°C (68-77°F). Do not refrigerate.
  • Available as Wild Berry Burst® Liquid. For adults and children 12 years and older.

This website contains current product information and may differ from the information on the product packaging you may have.


Directions

Do not take more than directed.

See overdose warning

  • mL = milliliter
  • use only enclosed dosing cup designed for use with this product. Do not use any other dosing device.

adults and children 12 years and over

  • take 30 mL in the dosing cup provided every 4 hours while symptoms last
  • do not take more than 150 mL in 24 hours, unless directed by a doctor

children under 12 years

ask a doctor

This website contains current product information and may differ from the information on the product packaging you may have. If you have any questions, please contact the Consumer Care Center at 1-877-895-3665. 


Reviews

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Questions + feedback

1-800-458-1635 (toll-free)

215-273-8755 (collect)

You can also reference our FAQs