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TYLENOL® vs Excedrin®<sup>¹</sup>

Both Excedrin® and TYLENOL® temporarily relieve minor aches and pains. TYLENOL®, which contains acetaminophen, can be a more appropriate option for those with stomach problems than Excedrin®, which contains a combination of the active ingredients, acetaminophen, aspirin and caffeine. Talk to your doctor if you have any questions and please note that the information below is not a substitute for the specific product's Drug Facts Label. Please always read and follow the label.

Explore our chart below to compare dosage information and active ingredients of Excedrin® vs. TYLENOL® to help you decide if TYLENOL® or Excedrin® is the best pain reliever for you.

Select 1 Product
Excedrin® 1
Characteristics
Forms Rapid Release Gels, Coated Tablets, Caplets Caplets, Geltabs
Active Ingredient Acetaminophen Acetaminophen/Aspirin/Caffeine
Dosing 2 pills every 6hrs while symptoms last; do not take more than 6 pills in 24 hours 2 pills every 6 hours; not more than 8 pills in 24 hours. Drink a full glass of water with each dose
Contains an NSAID
No
Yes
From the #1 Doctor-recommended Brand of Pain Reliever
Yes
No
Relieves Fever
Yes
No
Relieves Minor Back Pain/ Backache
Yes
No
Relieves Minor Headache
Yes
Yes
Relieves Minor Muscle Pain/ Muscle Aches
Yes
Yes
Relieves Minor Premenstrual and Menstrual Pain
Yes
Yes
Relieves Minor Toothache
Yes
Yes
Relieves Minor Arthritis Pain/ Joint Pain
Yes
Yes
Provides Fast Pain Relief
Yes
Yes
Works Centrally to Relieve Your Pain
Yes
Yes
May be more appropriate for those with High Blood Pressure, Kidney Disease, Stomach Problems, or Heart Disease
Yes
No
May cause severe stomach bleeding
No
Yes
Contains Liver Warning
Yes
2
Yes
3
1
Third-party trademarks used herein are trademarks of their respective owners.
2
Ask a doctor before use if you have liver disease. Severe liver damage may occur if you take more than 4,000 mg of acetaminophen in 24 hours, with other drugs containing acetaminophen, 3 or more alcoholic drinks every day while using this product.
3
Ask a doctor before use if you have liver cirrhosis.
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