Both Excedrin® and TYLENOL® temporarily relieve minor aches and pains. TYLENOL®, which contains acetaminophen, can be a more appropriate option than Excedrin®, which contains a combination of the active ingredients, acetaminophen, aspirin and caffeine. Talk to your doctor if you have any questions and please note that the information below is not a substitute for the specific product's Drug Facts Label. Please always read and follow the label.
Explore our chart below to compare dosage information and active ingredients of Excedrin® vs. TYLENOL® to help you decide if TYLENOL® or Excedrin® is the best pain reliever for you.
 <p class="mb-1">TYLENOL®</p><span class="h4">Extra Strength Caplets</span> |
 Excedrin® 1 |
|
|---|---|---|
| Characteristics | ||
| Forms | Rapid Release Gels, Coated Tablets, Caplets | Caplets, Geltabs |
| Active Ingredient | Acetaminophen | Acetaminophen / Aspirin / Caffeine |
| Dosing | 2 pills every 6hrs while symptoms last; do not take more than 6 pills in 24 hours | 2 pills every 6 hours; not more than 8 pills in 24 hours. Drink a full glass of water with each dose |
| Contains an NSAID |
No |
Yes |
| From the #1 Doctor-recommended Brand of Pain Reliever |
Yes |
No |
| Relieves Fever |
Yes |
No |
| Relieves Minor Back Pain/ Backache |
Yes |
No |
| Relieves Minor Headache |
Yes |
Yes |
| Relieves Minor Muscle Pain/ Muscle Aches |
Yes |
Yes |
| Relieves Minor Premenstrual and Menstrual Pain |
Yes |
Yes |
| Relieves Minor Toothache |
Yes |
Yes |
| Relieves Minor Arthritis Pain/ Joint Pain |
Yes |
Yes |
| Provides Fast Pain Relief |
Yes |
Yes |
| Works Centrally to Relieve Your Pain |
Yes |
Yes |
| May cause severe stomach bleeding |
No |
Yes |
| Contains Liver Warning |
Yes 2 |
Yes 3 |
1
Third-party trademarks used herein are trademarks of their respective owners.
2
Ask a doctor before use if you have liver disease. Severe liver damage may occur if you take more than 4,000 mg of acetaminophen in 24 hours, with other drugs containing acetaminophen, 3 or more alcoholic drinks every day while using this product.
3
Ask a doctor before use if you have liver cirrhosis.
Your first name and last initial will be displayed publicly to other users when you write a review or blog post (ex. ”John S.”).
Will be used as your user name
Registration permits you to participate in all areas of this site. By submitting your information above, you agree that the information you provide will be governed by our site's Privacy Policy.