• MOTRIN® Dual Action with TYLENOL®, Ibuprofen and Acetaminophen
  • MOTRIN® Dual Action with TYLENOL®, Ibuprofen and Acetaminophen
  • MOTRIN® Dual Action with TYLENOL®, Ibuprofen and Acetaminophen

MOTRIN® Dual Action with TYLENOL®

Ibuprofen and Acetaminophen - Two Medicines for Minor Aches & Pains, Ibuprofen (NSAID) 125 mg & Acetaminophen 250 mg

MOTRIN® Dual Action with TYLENOL®, 2-in-1 pain reliever tablets with the two medicines Ibuprofen and Acetaminophen for relief from minor aches and pains.

  • Dual action oral pain reliever combines two well-known pain medicines together for fast, effective relief
  • Temporarily relieves minor aches & pains due to headaches, toothaches, & backaches
  • Also relieves pain due to menstrual pains, period cramps, muscle aches, & minor arthritis pains

Each tablet contains 250 mg acetaminophen plus 125 mg NSAID ibuprofen (nonsteroidal anti-inflammatory drug). Adults and children 12 years of age and older should take two MOTRIN® Dual Action with TYLENOL® tablets every eight hours while symptoms persist.

Product details

Temporarily relieves minor aches and pains due to:

  • Headache
  • Toothache
  • Backache
  • Menstrual cramps
  • Muscular aches
  • Minor pain of arthritis

Active ingredients (in each tablet)
Acetaminophen 250 mg
Ibuprofen 125 mg (NSAID*) *nonsteroidal anti-inflammatory drug

Pain reliever

Inactive ingredients
Colloidal silicon dioxide, corn starch, croscarmellose sodium, crospovidone, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, povidone, pregelatinized starch, stearic acid, sucralose, talc, titanium dioxide

Do not use with other medicines containing ACETAMINOPHEN; can cause liver damage.

Acetaminophen liver damage warning: This product contains acetaminophen. Severe liver damage may occur if you take:

  • With other drugs containing acetaminophen
  • More than 6 tablets in 24 hours, which is the maximum daily amount for this product
  • 3 or more alcoholic drinks every day while using this product

Acetaminophen allergy alert: may cause severe skin reactions. Symptoms may include:

  • Skin reddening
  • Blisters
  • Rash

If skin reaction occurs, stop use and seek medical help right away.

NSAID allergy alert: ibuprofen may cause a severe allergic reaction, especially in people allergic to aspirin. Symptoms may include:

  • Hives
  • Facial swelling
  • Asthma (wheezing)
  • Shock
  • Skin reddening
  • Rash
  • Blisters

If an allergic reaction occurs, stop use and seek medical help right away.

NSAID stomach bleeding warning:This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you:

  • Are age 60 or older
  • Have had stomach ulcers or bleeding problems
  • Take a blood thinning (anticoagulant) or steroid drug
  • Take other drugs containing prescription or nonprescription NSAIDs [aspirin, ibuprofen, naproxen, or others]
  • Have 3 or more alcoholic drinks every day while using this product
  • Take more or for a longer time than directed

Heart attack and stroke warning: NSAIDs, except aspirin, increase the risk of heart attack, heart failure, and stroke. These can be fatal. The risk is higher if you use more than directed or for longer than directed.

Do not use

  • With any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist
  • If you have ever had an allergic reaction to acetaminophen or any other pain reliever
  • Right before or after heart surgery

Ask a doctor before use if

  • You have liver disease
  • Stomach bleeding warning applies to you
  • You have problems or serious side effects from taking pain relievers
  • You have a history of stomach problems, such as heartburn
  • You have high blood pressure, heart disease, liver cirrhosis, kidney disease, asthma, or had a stroke
  • You are taking a diuretic

Ask a doctor or pharmacist before use if you are

  • Under a doctor’s care for any serious condition
  • Taking aspirin for heart attack or stroke, because ibuprofen may decrease this benefit of aspirin
  • Taking any other drug

When using this product

  • Take with food or milk if stomach upset occurs

Stop use and ask a doctor if
You experience any of the following signs of stomach bleeding:

  • Feel faint
  • Vomit blood
  • Have bloody or black stools
  • Have stomach pain that does not get better

You have symptoms of heart problems or stroke:

  • Chest pain
  • Trouble breathing
  • Weakness in one part or side of body
  • Slurred speech
  • Leg swelling

Pain gets worse or lasts more than 10 days

Redness or swelling is present in the painful area

Any new symptoms appear

If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use ibuprofen at 20 weeks or later in pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery.

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222). Prompt medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Do not use if carton is opened. Do not use if foil inner seal imprinted with “SEALED for YOUR PROTECTION” is broken or missing.

  • Read all warnings and directions before use. Keep carton.
  • Store at 20-25°C (68-77°F)
  • Avoid excessive heat above 40°C (104°F)


Do not take more than directed.

adults and children 12 years and over

  • take 2 tablets every 8 hours while symptoms persist
  • do not take more than 6 tablets in 24 hours, unless directed by a doctor.

children under 12 years

ask a doctor


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