Skip to main content

TYLENOL® PM Extra Strength

Nighttime Pain Reliever & Sleep Aid, 500mg Acetaminophen & 25 mg Diphenhydramine HCl

Count
  • Provide minor pain relief and help you fall asleep fast

  • Non-habit forming when used as directed

  • Fall asleep fast and stay asleep and relieve minor pain with this nighttime sleep aid and pain relief medicine

  • Relieve nighttime pain and get the sleep you need with 25 mg diphenhydramine HCl and 500 mg acetaminophen per caplet

Product Details

Temporary relief of occasional headaches and minor aches and pains with accompanying sleeplessness

Active Ingredients (in each caplet)

Purpose

Acetaminophen 500 mg

Pain reliever

Diphenhydramine HCl 25 mg

Nighttime sleep aid

Inactive Ingredients

carnauba wax, crospovidone, FD&C blue no. 1 aluminum lake, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, povidone, pregelatinized starch, sodium starch glycolate, stearic acid, titanium dioxide

Do not take more than directed.

See overdose warning

Age

Dosage

Adults and children 12 years and over

• Take 2 caplets at bedtime
• Do not take more than 2 caplets of this product in 24 hours

Children under 12 years

Do not use

Liver warning:  This product contains acetaminophen. Severe liver damage may occur if you take

  • More than 4,000 mg of acetaminophen in 24 hours

  • With other drugs containing acetaminophen

  • 3 or more alcoholic drinks every day while using this product

Allergy alert:  acetaminophen may cause severe skin reactions. Symptoms may include:

  • Skin reddening

  • Blisters

  • Rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • With any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.

  • With any other product containing diphenhydramine, even one used on skin

  • In children under 12 years of age

  • If you have ever had an allergic reaction to this product or any of its ingredients

Ask a doctor before use if you have

  • Liver disease

  • A breathing problem such as emphysema or chronic bronchitis

  • Trouble urinating due to an enlarged prostate gland

  • Glaucoma

Ask a doctor or pharmacist before use if you are

  • Taking the blood thinning drug warfarin

  • Taking sedatives or tranquilizers

When using this product

  • Drowsiness will occur

  • Avoid alcoholic drinks

  • Do not drive a motor vehicle or operate machinery

Stop use and ask a doctor if

  • Sleeplessness persists continuously for more than 2 weeks. Insomnia may be a symptom of serious underlying medical illness.

  • Pain gets worse or lasts more than 10 days

  • Fever gets worse or lasts more than 3 days

  • Redness or swelling is present

  • New symptoms occur

These could be signs of a serious condition.

If pregnant or breast-feeding,  ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

  • Store between 20-25°C (68-77°F)

This website contains current product information and may differ from the information on the product packaging you may have.

FAQs

TYLENOL® PM Extra Strength is a nighttime pain reliever and sleep aid that relieves minor aches and pains and helps you fall asleep. The two key TYLENOL® PM ingredients in each caplet are:

  • Acetaminophen, 500 mg, for pain relief

  • Diphenhydramine HCl, 25 mg, a nighttime sleep aid

This combination helps relieve pain that may keep you awake while also helping you fall asleep and stay asleep.

TYLENOL® PM contains acetaminophen (not an NSAID, like ibuprofen or naproxen) as its pain reliever and diphenhydramine HCl as its sleep aid.

Because it doesn’t contain an NSAID (like ibuprofen, which is found in Advil PM, and naproxen, which is found in Aleve PM), TYLENOL® PM may be a good pain reliever/nighttime sleep aid option for those whom an NSAID may not be appropriate.

The TYLENOL® PM dosage for adults and children 12 years and older is 2 TYLENOL® PM Extra Strength caplets at bedtime. Do not take more than 2 caplets in 24 hours.

Stop use and ask a doctor if sleeplessness persists continuously for more than 2 weeks. Insomnia may be a symptom of serious underlying medical illness.

TYLENOL® PM provides temporary relief for occasional headaches and minor aches and pains that are accompanied by sleeplessness. These types of pain may include:

  • Headache

  • Minor aches and pains

If you’re looking for something to take when pain keeps you up at night, TYLENOL® PM can help relieve minor pains so you can fall asleep more easily.

No. TYLENOL® PM is non-habit forming when used as directed. Even though diphenhydramine can help you fall asleep if you have difficulty falling asleep, TYLENOL® PM is not considered habit-forming. Always read and follow the label.

TYLENOL® PM is specifically formulated for minor aches and pains with accompanying sleeplessness. Its combination of acetaminophen and a nighttime sleep aid relieves minor pain and helps you fall asleep.

Stop use and ask a doctor if pain gets worse or lasts more than 10 days.

TYLENOL® PM is formulated to help you fall asleep and stay asleep while relieving minor pain. Diphenhydramine in TYLENOL® PM is a nighttime sleep aid.

Don't see your question? Visit our FAQ page.

SEE ALL FAQS
Reviews