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General

Is TYLENOL® safe?

TYLENOL® is safe and effective when used as directed. The safety of TYLENOL® at recommended doses has been established through 50 years of use and scientific investigation. Do not exceed the recommended dosage as it may cause liver damage.

What is the active ingredient in TYLENOL®?

Acetaminophen is an active ingredient in all TYLENOL® products and in more than 600 other over-the-counter (OTC) and prescription medicines. Do not take more than one medicine containing acetaminophen at the same time.

How does TYLENOL® work?

TYLENOL® contains the active ingredient acetaminophen, which is a pain reliever and fever reducer. It works by elevating the body's overall pain threshold so you feel less pain, and lowers your fever by helping your body eliminate excess heat.

What is the definition of a fever?

A fever is the body’s response to a disease characterized by a rise in body temperature. A rectal temperature at or above 100.4⁰F, an oral temperature at or above 99.4⁰F, or an axillary temperature at or above 99⁰F is usually considered the threshold for a fever.

What is acetaminophen?

Acetaminophen is an effective pain reliever and fever reducer. Acetaminophen is thought to relieve mild to moderate pain by elevating your body’s overall pain threshold. It is also thought to lower your fever by helping your body eliminate excess heat.

What is Dextromethorphan HBR?

Dextromethorphan is a cough suppressant indicated for the temporary relief of cough due to the common cold/flu.

How does phenylephrine work?

Phenylephrine is a nasal decongestant indicated to help clear nasal passages, promote nasal and sinus drainage, and for temporary relief of sinus congestion and pressure.

What is guaifenesin?

Guaifenesin is an expectorant indicated to help loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive.

Does TYLENOL® contain aspirin?

No, TYLENOL® products do not contain aspirin.

Does TYLENOL® contain caffeine?

No, TYLENOL® products do not contain caffeine.

Should I take TYLENOL® with or without food?

You can take TYLENOL® with or without regard to meals.

What is the difference between TYLENOL® Cold & Flu Severe products and TYLENOL® Cold Multi-Symptom products?

Both TYLENOL® Cold & Flu Severe and TYLENOL® Cold & Flu and TYLENOL® Cold Multi-Symptom products contain acetaminophen, dextromethorphan, and phenylephrine. Therefore, both products can be used to temporarily reduce fever and are also indicated for the temporary relief of minor aches and pains, headache, sore throat, nasal congestion, cough, sinus congestion, and sinus pressure. Additionally, TYLENOL® Cold & Flu Severe products contain guaifenesin, an expectorant, which helps to relieve chest congestion and clear out mucus.

How are caplets, gelcaps, and geltabs different?

Easy-to-swallow caplets are solid capsule-shaped tablets coated with a water-soluble coating. Gelcaps are solid capsule-shaped tablets coated with smooth gelatin, making them easier to swallow. Geltabs are solid, rounded tablets coated with smooth gelatin.

How is TYLENOL® different from other brands of pain reliever?

Acetaminophen is the active ingredient in TYLENOL®. TYLENOL® products do not contain aspirin, ibuprofen or naproxen, the active ingredients found in other nonprescription pain relievers. Each of these active ingredients relieves pain, but they work differently.

Safety + Dosing

Can I use expired products?

We do not recommend using any products beyond their expiration date.  If your product has expired, please contact your local pharmacy to learn about how to properly discard it and obtain a new product.

Can I take a daytime product during the day and a nighttime product when I go to bed?

Yes, if you schedule your doses correctly and take no more than 5 total doses in 24 hours.  These products are to be used if you have symptoms. TYLENOL® Daytime products provide daytime relief for your cold and flu symptoms. Do not take TYLENOL® Daytime and Nighttime products at the same time and only use products that treat the symptom you have.  Always use TYLENOL® products as directed and read the entire product label before using.

Can I use a decongestant nasal spray while taking TYLENOL® Cold products?

No, TYLENOL® Cold or Sinus products contain a nasal decongestant.  Do not use two decongestants at the same time.

If I wake up in the middle of the night, can I take one more dose of nighttime cold products?

As stated on the product label, TYLENOL® products may be taken no sooner than every 4 hours after the last dose.  Always use TYLENOL® products as directed and read the product label.

Can TYLENOL® Cold or TYLENOL® Sinus products make me drowsy?

Only TYLENOL® Cold Multi-Symptom Liquid (Nighttime) contains doxylamine succinate, an antihistamine, which may cause marked drowsiness.  Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers.  Alcohol, sedatives, and tranquilizers may increase the drowsiness effect.   Always use the product as directed and read the label.

Can I drink alcohol and take TYLENOL®?

TYLENOL® contains acetaminophen. Severe liver damage may occur if you take 3 or more alcoholic drinks every day while using a TYLENOL® product.

Why can't I use TYLENOL® for more than 10 days?

The package label of all OTC pain medicines advise consumers to "stop use and ask a doctor if … pain gets worse or lasts more than 10 days…" This warning is necessary so that patients will seek appropriate medical attention if needed.

Does TYLENOL® cause liver damage?

The safety of TYLENOL® at recommended doses has been established through 50 years of use and scientific investigation; however, if you take too much, you could harm your liver.

In case of overdose, consumers are instructed to get medical help or contact a Poison Control Center right away. (1-800-222-1222). Quick medical attention is critical for adults as well as for children even if no signs or symptoms are noticed.

Can I take TYLENOL® with my other medications?

TYLENOL® should not be used with other products containing acetaminophen.

Ask a doctor or pharmacist before use if you are taking the blood-thinning drug warfarin.

Always read and follow the label.

If you are under a doctor’s care for any serious condition, or are taking any other drugs, you should talk to your doctor if you want to know more or have other questions.

Can TYLENOL® Cold or TYLENOL® Sinus products be taken with herbal supplements?

If you are taking any other drugs, including herbal supplements, you should talk to your doctor or pharmacist if you want to know more or have other questions. Always use the product as directed and read the label.

What can I do to soothe my cold while taking TYLENOL® Cold products?

In order to help soothe your cold while taking TYLENOL® Cold products, you should:

  • Get lots of rest, especially while you have a fever.  Rest helps your body fight illness.
  • Drink lots of fluids.  Soups and other fluids can help loosen mucus.
  • Soothe a sore throat by gargling with warm salt water or try throat sprays or lozenges.

Can I take TYLENOL® in between my doses of other pain relievers?

Use of TYLENOL® with other pain relievers (such as aspirin, ibuprofen, naproxen sodium, ketoprofen or prescription pain relievers) is not recommended, unless directed by your doctor.

Do not use TYLENOL® with any other products containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.

If you are under a doctor's care for any serious condition, or are taking any other drugs, you should talk to your doctor if you want to know more or have other questions.

Can TYLENOL® Cold and TYLENOL® Sinus caplets be crushed or broken?

No. TYLENOL® Cold and TYLENOL® Sinus caplets should be swallowed whole. Do not crush, chew, or dissolve the caplets in your mouth. Always use the product as directed and read the label.

Can my child take TYLENOL® Cold and/or TYLENOL® Sinus products?

TYLENOL® Cold and TYLENOL® Sinus products are indicated for adults and children 12 years and older. For children under 12 years, please ask your doctor.

Symptoms + Conditions

What types of pain and ailments can I use TYLENOL® for?

TYLENOL® (acetaminophen) is indicated for the reduction of fever and the temporary relief of minor aches and pains associated with:

  • The common cold
  • Headache
  • Toothache
  • Muscular aches
  • Backache
  • Minor pain of arthritis
  • Premenstrual and menstrual cramps

Does TYLENOL® help inflammation (swelling)?

Acetaminophen, the active ingredient in TYLENOL®, has not been shown to reduce inflammation.

Will TYLENOL® help my migraine headaches?

TYLENOL® (acetaminophen) is not indicated for migraine headaches

How do I know if I have a sinus headache, a cold, or the flu?

Sinus headaches are usually characterized by a throbbing pain in your forehead or behind your eyes that may increase when you lean forward or lie down. You may also experience pressure between your eyes or tenderness in your cheekbones, a sore throat, runny nose or cough. These symptoms may be a result of your nasal passages becoming swollen due to environmental irritants, allergies, or even a cold. As cold and flu symptoms can be very similar, please refer to the following differences:

A cold is characterized by a runny nose, watery eyes, stuffy nose, and congestion, sneezing and coughing. These symptoms build over 48 hours and may last for 3-10 days. Unlike the cold, flu symptoms such as fever and chills appear very quickly and may last for 7-14 days (and may linger for up to 3 weeks). Other symptoms include body aches and pains, weakness and fatigue.

Can I take TYLENOL® with my existing medical condition?

If you are under a doctor's care for any serious condition, or are taking any other drugs, you should talk to your doctor if you want to know more or have other questions.

Can I take TYLENOL® if I have liver disease?

Talk to a doctor or pharmacist before use if you have liver disease.

Pregnancy + Children

Can I take TYLENOL® if I am pregnant or nursing?

If you are pregnant or nursing a baby, seek the advice of your healthcare professional before using TYLENOL® or any other medication.