When was TYLENOL® first introduced?

TYLENOL® was first introduced in 1955 as a children's fever reducer and pain reliever.

What is TYLENOL® known for?

TYLENOL® is known for providing pain relief and fever reduction products, including many products containing acetaminophen and other pain-relieving options trusted by families for more than 70 years.

How has TYLENOL® innovated over the years?

TYLENOL® has introduced innovations including , , and , tamper-evident packaging, and .

What is TYLENOL® with Naproxen?

is the first and only FDA-approved over-the-counter pain reliever that combines 650 mg of acetaminophen and 220 mg of naproxen sodium in a fixed-dose. It’s indicated for the temporary relief of minor aches and pains and is available without a prescription.

Our Story: 70 Years+ of Trusted Relief

More Than 70 Years of Trusted Relief

For more than 70 years, TYLENOL® has helped people care for themselves and the ones they love through life's everyday aches, pains, and fevers.

TYLENOL® products are built around acetaminophen, a trusted pain reliever and fever reducer used by millions of people.

What began as a children's fever reducer and pain reliever in 1955 has grown into one of the world's most recognized over-the-counter pain relief brands. Along the way, we've continued to innovate with one goal in mind: helping make pain and fever relief more accessible, convenient, and trusted.

Built Around People's Needs

The TYLENOL® story starts with listening.

From parents caring for a child with a fever to adults seeking trusted pain relief, people have helped shape our journey.

As those expectations evolved, so did TYLENOL®, expanding from children's products into a broad range of solutions for families.

That commitment continues to inspire innovations for children and adults, nighttime pain relief, targeted topical relief, and new ways to help people manage pain throughout the day.

Innovating Through the Decades

Innovation has helped shape the TYLENOL® story for decades. From introducing Extra Strength TYLENOL® to developing formats like Rapid Release Gels and targeted options like TYLENOL® PRECISE®, we've continued to evolve alongside people's changing needs.

We've also helped advance safety standards, introducing tamper-evident packaging in 1982 and continuing our commitment to helping consumers use our products confidently and responsibly.

Continuing Our Legacy of Innovation

More than seven decades after introducing our first product, we continue to build on our history of innovation.

In 2026, TYLENOL® introduced TYLENOL® with Naproxen, the first and only FDA-approved over-the-counter combination of acetaminophen and naproxen sodium, offering a new option for fast, long-lasting pain relief.

As needs continue to change, our commitment remains the same: listening to people and creating meaningful innovations that help support everyday care.

Today, TYLENOL® remains committed to helping people care for themselves and their families through trusted products, meaningful innovation, and resources that support responsible use.

Key Milestones

The milestones below highlight some of the key moments that have shaped the TYLENOL® story over the past seven decades.

1955

TYLENOL® launches as a children’s fever reducer and pain reliever.

1959

TYLENOL® becomes available over the counter.

1961

Adult TYLENOL® is introduced.

1975

Extra Strength TYLENOL® launches.

1982

TYLENOL® helps pioneer tamper-evident packaging that later became an industry standard.

1990s-2000s

TYLENOL® expands with solutions like TYLENOL® PM and TYLENOL® Cold + Flu products.

2010s-2020s

TYLENOL® introduces innovations including Rapid Release Gels and TYLENOL® PRECISE®.

2026

TYLENOL® with Naproxen launches as the first FDA-approved OTC combination of acetaminophen and naproxen sodium, marking a new chapter in OTC pain relief.

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