Extra Strength TYLENOL® Cold + Flu Multi-Symptom Relief Value Combo Pack
With acetaminophen for aches, pain and fever. Relieves multiple cold & flu symptoms
Contains one 8-fluid ounce bottle of non-drowsy daytime relief medicine and one 8-fluid ounce bottle of night relief medicine
Formulated to temporarily reduce fevers & relieve common cold or flu symptoms such as minor body aches & pains, headache, sore throat & cough
For fast non-drowsy day-time multi-symptom relief, that helps relieve cold+flu symptoms such as head+body aches, fever, sore throat with an added cooling cherry flavor.
From the #1 doctor recommended pain relief brand*
Liquid cold medicine can be used by adults and children 12 years and older for cough and sore throat relief
*Based on survey IQVIA 2025
Product Details
TYLENOL® Extra Strength Cold + Flu Multi-Symptom Day Liquid
Temporarily:
Reduces fever
Relieves these common cold/flu symptoms:
Minor aches and pains
Headache
Sore throat
Cough
TYLENOL® Extra Strength Cold + Flu Multi-Symptom Night Liquid
Temporarily:
Reduces fever
Relieves these common cold/flu symptoms:
Minor aches and pains
Headache
Sore throat
Cough
Sneezing and runny nose
TYLENOL® Extra Strength Cold + Flu Multi-Symptom Day Liquid
Active Ingredients | Purpose |
|---|---|
Acetaminophen 1,000 mg | Pain reliever/fever reducer |
Dextromethorphan HBr 30 mg | Cough suppressant |
Inactive Ingredients
anhydrous citric acid, carboxymethylcellulose sodium, FD&C red no 40, flavors, glycerin, microcrystalline cellulose and carboxymethylcellulose sodium, poloxamer, polyethylene glycol, propylene glycol, purified water, sodium benzoate, sorbitol, sucralose
TYLENOL® Extra Strength Cold + Flu Multi-Symptom Night Liquid
Active Ingredients | Purpose |
|---|---|
Acetaminophen 1,000 mg | Pain reliever/fever reducer |
Dextromethorphan HBr 30 mg | Cough suppressant |
Doxylamine succinate 12.5 mg | Antihistamine |
Inactive Ingredients
anhydrous citric acid, carboxymethylcellulose sodium, FD&C blue no. 1, FD&C red no. 40, flavors, glycerin, microcrystalline cellulose and carboxymethylcellulose sodium, poloxamer, polyethylene glycol, propylene glycol, purified water, sodium benzoate, sorbitol, sucralose
TYLENOL® Extra Strength Cold + Flu Multi-Symptom Day Liquid
Do not take more than directed.
See overdose warning
Shake well before using
mL = milliliter
Use only enclosed dosing cup designed for use with this product. Do not use any other dosing device.
Age | Dosage |
|---|---|
Adults and children 12 years and over | • Take 30 mL in the dosing cup provided every 6 hours while symptoms last • Do not take more than 90 mL in 24 hours, unless directed by a doctor • Do not use for more than 10 days unless directed by a doctor |
Children under 12 years | Ask a doctor |
TYLENOL® Extra Strength Cold + Flu Multi-Symptom Night Liquid
Do not take more than directed.
See overdose warning
Shake well before using
mL = milliliter
Use only enclosed dosing cup designed for use with this product. Do not use any other dosing device.
Age | Dosage |
|---|---|
Adults and children 12 years and over | • Take 30 mL in the dosing cup provided every 6 hours while symptoms last • Do not take more than 90 mL in 24 hours, unless directed by a doctor • Do not use for more than 10 days unless directed by a doctor |
Children under 12 years | Ask a doctor |
TYLENOL® Extra Strength Cold + Flu Multi-Symptom Day Liquid
Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take
More than 4,000 mg of acetaminophen in 24 hours
With other drugs containing acetaminophen
3 or more alcoholic drinks every day while using this product
Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:
skin reddening
blisters
rash
If a skin reaction occurs, stop use and seek medical help right away.
Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.
Do not use
With any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
If you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
If you have ever had an allergic reaction to this product or any of its ingredients
Ask a doctor before use if you have
Liver disease
Persistent or chronic cough such as occurs with smoking, asthma or emphysema
Cough that occurs with too much phlegm (mucus)
Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin
When using this product do not exceed recommended dose
Stop use and ask a doctor if
Pain or cough gets worse or lasts more than 7 days
Fever gets worse or lasts more than 3 days
Redness or swelling is present
New symptoms occur
Cough comes back or occurs with rash or headache that lasts
These could be signs of a serious condition.
If pregnant or breast-feeding, ask a health professional before use.
Keep out of reach of children .
Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.
TYLENOL® Extra Strength Cold + Flu Multi-Symptom Night Liquid
Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take
More than 4,000 mg of acetaminophen in 24 hours
With other drugs containing acetaminophen
3 or more alcoholic drinks every day while using this product
Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:
skin reddening
blisters
rash
If a skin reaction occurs, stop use and seek medical help right away.
Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.
Do not use
With any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
If you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
If you have ever had an allergic reaction to this product or any of its ingredients
Ask a doctor before use if you have
Liver disease
A breathing problem such as emphysema or chronic bronchitis
Glaucoma
Trouble urinating due to an enlarged prostate gland
Persistent or chronic cough such as occurs with smoking, asthma or emphysema
Cough that occurs with too much phlegm (mucus)
Ask a doctor or pharmacist before use if you are
Taking the blood thinning drug warfarin
Taking sedatives or tranquilizers
When using this product
Do not exceed recommended dose
Excitability may occur, especially in children
Marked drowsiness may occur
Alcohol, sedatives and tranquilizers may increase drowsiness
Avoid alcoholic drinks
Be careful when driving a motor vehicle or operating machinery
Stop use and ask a doctor if
Pain or cough gets worse or lasts more than 7 days
Fever gets worse or lasts more than 3 days
Redness or swelling is present
New symptoms occur
Cough comes back or occurs with rash or headache that lasts
These could be signs of a serious condition.
If pregnant or breast-feeding, ask a health professional before use.
Keep out of reach of children .
Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.
Each 30 mL contains: sodium 19 mg
Store between 20-25°C (68-77°F)
Do not use if neck band imprinted with “INSTANT COOLING SENSATION” or foil inner seal imprinted with “TYLENOL” is broken or missing
This website contains current product information and may differ from the information on the product packaging you may have.
Related Products
FSA/HSA Eligible
TYLENOL® Extra Strength Cold + Flu Multi-Symptom Daytime Liquid
FSA/HSA Eligible

