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Cardiovascular Disease and Pain Relief

Cardiovascular Disease and Pain Relief

The American Heart Association identifies acetaminophen (TYLENOL®) as a pain relief option to try first* for patients with, or at high risk for, cardiovascular disease, as it is not known to increase risks of heart attack, heart failure, or stroke.

NSAIDs, like ibuprofen (e.g. Advil®, MOTRIN®) and naproxen sodium (e.g. Aleve®), may increase the risk of heart attack, heart failure, and stroke. The risk is higher if you use more than directed or for longer than directed. Stop use and ask your doctor if you have symptoms of heart problems or stroke, while taking OTC ibuprofen or naproxen sodium.

*When symptoms are not controlled by non-pharmacological approaches


A variety of factors contribute to your risk of cardiovascular disease.

A variety of factors contribute to your risk of cardiovascular disease. Your doctor can use these factors to help identify your personal level of risk. Some major risk factors include:

High Cholesterol

A family history of cardiovascular disease

High blood pressure

Tobacco us

Age, especially over 65 years old

Diabetes

Race (certain minority groups have higher risk of heart disease than Caucasians)

Male sex

Obesity / overweight

Health Condition
High Blood Pressure
Aspirin Heart Therapy
Acetaminophen(TYLENOL®)
TYLENOL® does not interfere with certain blood pressure control medications the way NSAIDs sometimes can.
For people on aspirin heart therapy, TYLENOL® is the brand of pain reliever recommended most often by doctors, more than all other brands combined

It does not interfere with aspirin’s ability to protect against heart attack or stroke, like ibuprofen (e.g. Advil®, MOTRIN®) or naproxen sodium (e.g. Aleve®) can.

Health Condition & Acetaminophen(TYLENOL®)
High Blood Pressure
TYLENOL® does not interfere with certain blood pressure control medications the way NSAIDs sometimes can.
Aspirin Heart Therapy
For people on aspirin heart therapy, TYLENOL® is the brand of pain reliever recommended most often by doctors, more than all other brands combined. It does not interfere with aspirin’s ability to protect against heart attack or stroke, like ibuprofen (e.g. Advil®, MOTRIN®) or naproxen sodium (e.g. Aleve®) can.

See information for people taking high blood pressure medicine.

Learn more about product information.

Learn how TYLENOL® may be an appropriate pain reliever for you.